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GPER limits adverse changes to Ca(2+) signalling and arrhythmogenic activity in ovariectomised guinea pig cardiomyocytes

Background: The increased risk of post-menopausal women developing abnormalities of heart function emphasises the requirement to understand the effect of declining oestrogen levels on cardiac electrophysiology and structure, and investigate possible therapeutic targets, namely the G protein-coupled...

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Detalles Bibliográficos
Autores principales: Francis, Alice J., Firth, Jahn M., Sanchez-Alonso, Jose L., Gorelik, Julia, MacLeod, Kenneth T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686394/
https://www.ncbi.nlm.nih.gov/pubmed/36439245
http://dx.doi.org/10.3389/fphys.2022.1023755