Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old mice

Total body irradiation (TBI) is a commonly used conditioning regimen for hematopoietic stem cell transplant (HCT), but dose heterogeneity and long-term organ toxicity pose significant challenges. Total marrow irradiation (TMI), an evolving radiation conditioning regimen for HCT can overcome the limi...

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Detalles Bibliográficos
Autores principales: Lim, Ji Eun, Sargur Madabushi, Srideshikan, Vishwasrao, Paresh, Song, Joo Y., Abdelhamid, Amr M. H., Ghimire, Hemendra, Vanishree, V. L., Lamba, Jatinder K., Dandapani, Savita, Salhotra, Amandeep, Lemecha, Mengistu, Pierini, Antonio, Zhao, Daohong, Storme, Guy, Holtan, Shernan, Aristei, Cynthia, Schaue, Dorthe, Al Malki, Monzr, Hui, Susanta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686437/
https://www.ncbi.nlm.nih.gov/pubmed/36439420
http://dx.doi.org/10.3389/fonc.2022.1045016

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