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Flow Synthesis of Nature-Inspired Mitochondria-Targeted Phenolic Derivatives as Potential Neuroprotective Agents
A series of phenolic derivatives designed to selectively target mitochondria were synthesized under flow conditions starting from natural phenolic acids. The two-step continuous flow protocol, performed in Cyrene, a bioavailable dipolar aprotic solvent, allowed the isolation of the MITO compounds in...
Autores principales: | Pecora, Desirée, Annunziata, Francesca, Pegurri, Sergio, Picone, Pasquale, Pinto, Andrea, Nuzzo, Domenico, Tamborini, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686576/ https://www.ncbi.nlm.nih.gov/pubmed/36358530 http://dx.doi.org/10.3390/antiox11112160 |
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