Effect of Empagliflozin on Thioacetamide-Induced Liver Injury in Rats: Role of AMPK/SIRT-1/HIF-1α Pathway in Halting Liver Fibrosis

Hepatic fibrosis causes severe morbidity and death. No viable treatment can repair fibrosis and protect the liver until now. We intended to discover the empagliflozin’s (EMPA) hepatoprotective efficacy in thioacetamide (TAA)-induced hepatotoxicity by targeting AMPK/SIRT-1 activity and reducing HIF-1...

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Detalles Bibliográficos
Autores principales: ElBaset, Marwan A., Salem, Rana S., Ayman, Fairouz, Ayman, Nadeen, Shaban, Nooran, Afifi, Sherif M., Esatbeyoglu, Tuba, Abdelaziz, Mahmoud, Elalfy, Zahraa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686640/
https://www.ncbi.nlm.nih.gov/pubmed/36358524
http://dx.doi.org/10.3390/antiox11112152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686640/
https://www.ncbi.nlm.nih.gov/pubmed/36358524
http://dx.doi.org/10.3390/antiox11112152

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