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Dexmedetomidine Attenuates Apoptosis and Neurological Deficits by Modulating Neuronal NADPH Oxidase 2-Derived Oxidative Stress in Neonates Following Hypoxic Brain Injury

Hypoxic–ischemic brain injury is an important cause of neonatal neurological deficits. Our previous study demonstrated that dexmedetomidine (Dex) provided neuroprotection against neonatal hypoxic brain injury; however, the underlying mechanisms remain incompletely elucidated. Overactivation of NADPH...

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Detalles Bibliográficos
Autores principales: Chen, Xiaohui, Chen, Dongtai, Chen, Pinzhong, Chen, Andi, Deng, Jianhui, Wei, Jianjie, Zeng, Weian, Zheng, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686745/
https://www.ncbi.nlm.nih.gov/pubmed/36358571
http://dx.doi.org/10.3390/antiox11112199