Oral Administration of Glutathione Trisulfide Increases Reactive Sulfur Levels in Dorsal Root Ganglion and Ameliorates Paclitaxel-Induced Peripheral Neuropathy in Mice

Peripheral neuropathy is a dose-limiting side effect of chemotherapy with paclitaxel. Paclitaxel-induced peripheral neuropathy (PIPN) is typically characterized by a predominantly sensory neuropathy presenting with allodynia, hyperalgesia and spontaneous pain. Oxidative mitochondrial damage in perip...

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Detalles Bibliográficos
Autores principales: Ezaka, Mariko, Marutani, Eizo, Miyazaki, Yusuke, Kanemaru, Eiki, Selig, Martin K., Boerboom, Sophie L., Ostrom, Katrina F., Stemmer-Rachamimov, Anat, Bloch, Donald B., Brenner, Gary J., Ohshima, Etsuo, Ichinose, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686764/
https://www.ncbi.nlm.nih.gov/pubmed/36358494
http://dx.doi.org/10.3390/antiox11112122

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