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Immune escape pathways from the HBV core(18-27) CD8 T cell response are driven by individual HLA class I alleles
BACKGROUND AND AIMS: There is growing interest in T cell-based immune therapies for a functional cure of chronic HBV infection including check-point inhibition, T cell-targeted vaccines or TCR-grafted effector cells. All these approaches depend on recognition of HLA class I-presented viral peptides....
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686862/ https://www.ncbi.nlm.nih.gov/pubmed/36439181 http://dx.doi.org/10.3389/fimmu.2022.1045498 |