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Methylglyoxal-Modified Human Serum Albumin Binds to Leukocyte Myeloperoxidase and Inhibits its Enzymatic Activity

Hyperglycemia in diabetes mellitus induces modification of proteins by glucose and its derivative methylglyoxal (MG). Neutrophils perform their bactericidal activity mainly via reactive halogen (RHS) and oxygen (ROS) species generation catalyzed by myeloperoxidase (MPO) stored in neutrophil azurophi...

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Detalles Bibliográficos
Autores principales:	Panasenko, Oleg M., Ivanov, Viktor A., Mikhalchik, Elena V., Gorudko, Irina V., Grigorieva, Daria V., Basyreva, Liliya Yu., Shmeleva, Ekaterina V., Gusev, Sergey A., Kostevich, Valeria A., Gorbunov, Nikolay P., Sokolov, Alexey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686918/ https://www.ncbi.nlm.nih.gov/pubmed/36421449 http://dx.doi.org/10.3390/antiox11112263

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