Targeting PARK7 Improves Acetaminophen-Induced Acute Liver Injury by Orchestrating Mitochondrial Quality Control and Metabolic Reprogramming

Mitochondrial dysfunction and oxidative stress are considered to be key events in acetaminophen (APAP)-induced acute liver injury. Mitochondrial quality control, including mitophagy and mitochondrial synthesis, can restore mitochondrial homeostasis and thus protect the liver. The role of PARK7, a mi...

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Detalles Bibliográficos
Autores principales: Cai, Jiao, Kong, Deqin, Long, Zi, Liu, Jiangzheng, Liu, Rui, Hai, Chunxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686963/
https://www.ncbi.nlm.nih.gov/pubmed/36358500
http://dx.doi.org/10.3390/antiox11112128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686963/
https://www.ncbi.nlm.nih.gov/pubmed/36358500
http://dx.doi.org/10.3390/antiox11112128

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