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Fosfomycin Pharmacokinetic Profile in Plasma and Urine and Quantitative Estimation in Prostate and Seminal Vesicles after One and Two Consecutive Doses of Oral Fosfomycin Trometamol in Healthy Male Volunteers
The present Phase I study investigated, for the first time, fosfomycin pharmacokinetics in humans after two 3 g doses of fosfomycin trometamol administered 27 h apart, according to the dose regimen recommended for the prophylactic indication for transrectal prostate biopsy in adult men. Plasma, urin...
Autores principales: | Di Stefano, Andrea F. D., Radicioni, Milko M., Morano, Francesca, Gentili, Alessandra, Mallat, Elena, Cuomo, Dario, Mazzarella, Tonia, Di Fonzo, Veronica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687076/ https://www.ncbi.nlm.nih.gov/pubmed/36358113 http://dx.doi.org/10.3390/antibiotics11111458 |
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