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TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome
Harnessing the innate power of T cells for therapeutic benefit has seen many shortcomings due to cytotoxicity in the past, but still remains a very attractive mechanism of action for immune-modulating biotherapeutics. With the intent of expanding the therapeutic window for T-cell targeting biotherap...
Autores principales: | Carrara, Stefania C., Harwardt, Julia, Grzeschik, Julius, Hock, Björn, Kolmar, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687101/ https://www.ncbi.nlm.nih.gov/pubmed/36439165 http://dx.doi.org/10.3389/fimmu.2022.1051875 |
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