Cargando…
Challenges and Strategies for a Thorough Characterization of Antibody Acidic Charge Variants
Heterogeneity of therapeutic Monoclonal antibody (mAb) drugs are due to protein variants generated during the manufacturing process. These protein variants can be critical quality attributes (CQAs) depending on their potential impact on drug safety and/or efficacy. To identify CQAs and ensure the dr...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687119/ https://www.ncbi.nlm.nih.gov/pubmed/36354552 http://dx.doi.org/10.3390/bioengineering9110641 |