Combination Therapy of Curcumin and Disulfiram Synergistically Inhibits the Growth of B16-F10 Melanoma Cells by Inducing Oxidative Stress

Oxidative stress plays a central role in the pathophysiology of melanoma. Curcumin (CUR) is a polyphenolic phytochemical that stimulates reactive oxygen species (ROS) production, while disulfiram (DSS) is a US FDA-approved drug for the treatment of alcoholism that can act by inhibiting the intracell...

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Detalles Bibliográficos
Autores principales: Fontes, Sheila S., Nogueira, Mateus L., Dias, Rosane B., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Vannier-Santos, Marcos A., Bezerra, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687191/
https://www.ncbi.nlm.nih.gov/pubmed/36358950
http://dx.doi.org/10.3390/biom12111600

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