Cargando…
The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases
The study investigated allogenic pulp transplantation as an innovative method of regenerative endodontic therapy. Three patients were selected for the endodontic treatment of single-root teeth, who also had a son/daughter with deciduous teeth or third molars scheduled for extraction. Receptor teeth...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687239/ https://www.ncbi.nlm.nih.gov/pubmed/36421100 http://dx.doi.org/10.3390/bioengineering9110699 |
_version_ | 1784835954710675456 |
---|---|
author | Feitosa, Victor Pinheiro Mota, Mara Natiere Savoldi, Roseane Rifane, Tainah de Paula, Diego Borges, Livia Solheiro, Luzia Kelly Aguiar Neto, Manoel Vieira, Lorena Moreira, Ana Carolina Sauro, Salvatore |
author_facet | Feitosa, Victor Pinheiro Mota, Mara Natiere Savoldi, Roseane Rifane, Tainah de Paula, Diego Borges, Livia Solheiro, Luzia Kelly Aguiar Neto, Manoel Vieira, Lorena Moreira, Ana Carolina Sauro, Salvatore |
author_sort | Feitosa, Victor Pinheiro |
collection | PubMed |
description | The study investigated allogenic pulp transplantation as an innovative method of regenerative endodontic therapy. Three patients were selected for the endodontic treatment of single-root teeth, who also had a son/daughter with deciduous teeth or third molars scheduled for extraction. Receptor teeth were endodontically instrumented and irrigated using a tri-antibiotic solution. During the transplant procedures, the teeth from the son/daughter were extracted, sectioned, and the pulp was carefully removed. The harvested pulp from the donor was inserted into the root canal of the host tooth (father/mother), followed by direct pulp capping and resin composite restoration. The teeth were followed-up with for 2 years and were surveyed with computed tomography, the electric pulp vitality test, and Doppler ultrasound examination. At the 6-month follow-up, positive pulp vitality and the formation of periapical lesions were verified in cases 1 and 2. Case 3 showed remarkable periapical radiolucency before transplantation, but after 1 year, such lesions disappeared and there was positive vitality. All teeth were revascularized as determined by Doppler imaging after 2 years with no signs of endodontic/periodontal radiolucency. In conclusion, although this was a case series with only three patients and four teeth treated, it is possible to suppose that this allogenic pulp transplantation protocol could represent a potential strategy for pulp revitalization in specific endodontic cases. |
format | Online Article Text |
id | pubmed-9687239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96872392022-11-25 The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases Feitosa, Victor Pinheiro Mota, Mara Natiere Savoldi, Roseane Rifane, Tainah de Paula, Diego Borges, Livia Solheiro, Luzia Kelly Aguiar Neto, Manoel Vieira, Lorena Moreira, Ana Carolina Sauro, Salvatore Bioengineering (Basel) Case Report The study investigated allogenic pulp transplantation as an innovative method of regenerative endodontic therapy. Three patients were selected for the endodontic treatment of single-root teeth, who also had a son/daughter with deciduous teeth or third molars scheduled for extraction. Receptor teeth were endodontically instrumented and irrigated using a tri-antibiotic solution. During the transplant procedures, the teeth from the son/daughter were extracted, sectioned, and the pulp was carefully removed. The harvested pulp from the donor was inserted into the root canal of the host tooth (father/mother), followed by direct pulp capping and resin composite restoration. The teeth were followed-up with for 2 years and were surveyed with computed tomography, the electric pulp vitality test, and Doppler ultrasound examination. At the 6-month follow-up, positive pulp vitality and the formation of periapical lesions were verified in cases 1 and 2. Case 3 showed remarkable periapical radiolucency before transplantation, but after 1 year, such lesions disappeared and there was positive vitality. All teeth were revascularized as determined by Doppler imaging after 2 years with no signs of endodontic/periodontal radiolucency. In conclusion, although this was a case series with only three patients and four teeth treated, it is possible to suppose that this allogenic pulp transplantation protocol could represent a potential strategy for pulp revitalization in specific endodontic cases. MDPI 2022-11-17 /pmc/articles/PMC9687239/ /pubmed/36421100 http://dx.doi.org/10.3390/bioengineering9110699 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Feitosa, Victor Pinheiro Mota, Mara Natiere Savoldi, Roseane Rifane, Tainah de Paula, Diego Borges, Livia Solheiro, Luzia Kelly Aguiar Neto, Manoel Vieira, Lorena Moreira, Ana Carolina Sauro, Salvatore The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title | The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title_full | The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title_fullStr | The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title_full_unstemmed | The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title_short | The Allogenic Dental Pulp Transplantation from Son/Daughter to Mother/Father: A Follow-Up of Three Clinical Cases |
title_sort | allogenic dental pulp transplantation from son/daughter to mother/father: a follow-up of three clinical cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687239/ https://www.ncbi.nlm.nih.gov/pubmed/36421100 http://dx.doi.org/10.3390/bioengineering9110699 |
work_keys_str_mv | AT feitosavictorpinheiro theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT motamaranatiere theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT savoldiroseane theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT rifanetainah theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT depauladiego theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT borgeslivia theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT solheiroluziakelly theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT aguiarnetomanoel theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT vieiralorena theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT moreiraanacarolina theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT saurosalvatore theallogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT feitosavictorpinheiro allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT motamaranatiere allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT savoldiroseane allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT rifanetainah allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT depauladiego allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT borgeslivia allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT solheiroluziakelly allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT aguiarnetomanoel allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT vieiralorena allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT moreiraanacarolina allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases AT saurosalvatore allogenicdentalpulptransplantationfromsondaughtertomotherfatherafollowupofthreeclinicalcases |