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Exploiting DNA Replication Stress as a Therapeutic Strategy for Breast Cancer

Proliferating cells rely on DNA replication to ensure accurate genome duplication. Cancer cells, including breast cancer cells, exhibit elevated replication stress (RS) due to the uncontrolled oncogenic activation, loss of key tumor suppressors, and defects in the DNA repair machinery. This intrinsi...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Chan, Doug W., Lin, Shiaw-Yih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687274/ https://www.ncbi.nlm.nih.gov/pubmed/36359297 http://dx.doi.org/10.3390/biomedicines10112775

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