Cargando…

Novel Chromone-Containing Allylmorpholines Induce Anxiolytic-like and Sedative Effects in Adult Zebrafish

Chromone-containing allylmorpholines (CCAMs) are a novel class of compounds that have demonstrated acetyl- and butyryl-cholinesterase-inhibiting and N-methyl-D-aspartate (NMDA) receptor-blocking properties in vitro, but their in vivo pharmacological activity remains underexplored. In this work, we e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prikhodko, Veronika A., Sysoev, Yuri I., Gerasimova, Elena V., Okovityi, Sergey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687339/ https://www.ncbi.nlm.nih.gov/pubmed/36359303 http://dx.doi.org/10.3390/biomedicines10112783

Ejemplares similares

Chromone-Containing Allylmorpholines Influence Ion Channels in Lipid Membranes via Dipole Potential and Packing Stress
por: Efimova, Svetlana S., et al.
Publicado: (2022)

Color-Coding Method Reveals Enhancement of Stereotypic Locomotion by Phenazepam in Rat Open Field Test
por: Makarov, Mark, et al.
Publicado: (2023)

Potential Drug Candidates to Treat TRPC6 Channel Deficiencies in the Pathophysiology of Alzheimer’s Disease and Brain Ischemia
por: Prikhodko, Veronika, et al.
Publicado: (2020)

4-Allylmorpholin-4-ium bromide
por: Han, Meng Ting
Publicado: (2012)

Effects of Alpha-2 Adrenergic Agonist Mafedine on Brain Electrical Activity in Rats after Traumatic Brain Injury
por: Sysoev, Yuriy I., et al.
Publicado: (2021)

Changes in Brain Electrical Activity after Transient Middle Cerebral Artery Occlusion in Rats
por: Sysoev, Yuriy I., et al.
Publicado: (2022)

Pharmacotherapy for Non-Alcoholic Fatty Liver Disease: Emerging Targets and Drug Candidates
por: Prikhodko, Veronika A., et al.
Publicado: (2022)

Anticonvulsant, Anxiolytic, and Sedative Activities of Verbena officinalis
por: Khan, Abdul Waheed, et al.
Publicado: (2016)

SGLT2 Inhibitor Empagliflozin Modulates Ion Channels in Adult Zebrafish Heart
por: Karpushev, Alexey V., et al.
Publicado: (2022)

Anxiolytics, Sedatives, and Hypnotics Prescribed by Dentists in Brazil in 2010
por: Lino, Patrícia Azevedo, et al.
Publicado: (2017)

Attenuation of neurological deficit by a novel ethanolamine derivative in rats after brain trauma
por: Sysoev, Yuriy Igorevich, et al.
Publicado: (2019)

Sedative and Anxiolytic-Like Actions of Ethanol Extract of Leaves of Glinus oppositifolius (Linn.) Aug. DC.
por: Moniruzzaman, Md., et al.
Publicado: (2016)

Anxiolytic-Like and Sedative Effects of Alcea Aucheri (Boiss.) Alef. Flower Extract in the Laboratory Rat
por: Mombeini, Tajmah, et al.
Publicado: (2017)

Antibacterial activity and anxiolytic-like effect of Ziziphus joazeiro Mart. leaves in adult zebrafish (Danio rerio)
por: de Souza, Antônio Barros, et al.
Publicado: (2023)

Anxiolytic effects of silibinin and naringenin on zebrafish model: A preclinical study
por: Nachammai, V., et al.
Publicado: (2021)

Anxiolytic, sedative, and hypnotic activities of aqueous extract of Morinda citrifolia fruit
por: Kannan, Sridharan, et al.
Publicado: (2014)

Commentary: Establishing zebrafish as a model to study the anxiolytic effects of scopolamine
por: de Abreu, Murilo S., et al.
Publicado: (2018)

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus Lippia L. Species
por: Nonato, Carla de Fatima Alves, et al.
Publicado: (2023)

Anxiolytic effects of fluoxetine and nicotine exposure on exploratory behavior in zebrafish
por: Singer, Matthew L., et al.
Publicado: (2016)

Establishing zebrafish as a model to study the anxiolytic effects of scopolamine
por: Hamilton, Trevor J., et al.
Publicado: (2017)

Synthesis, Anticonvulsant, Sedative and Anxiolytic Activities of Novel Annulated Pyrrolo[1,4]benzodiazepines
por: Sorra, Kumaraswamy, et al.
Publicado: (2014)

Sedative and Anxiolytic Activities of Opuntia ficus indica (L.) Mill.: An Experimental Assessment in Mice
por: Akkol, Esra Küpeli, et al.
Publicado: (2020)

Synthesis of Chromone-Related Pyrazole Compounds
por: Santos, Clementina M. M., et al.
Publicado: (2017)

Chromone and Flavonoid Alkaloids: Occurrence and Bioactivity
por: Khadem, Shahriar, et al.
Publicado: (2011)

Anxiolytic-like effects of Pseudospondias microcarpa hydroethanolic leaf extract in zebrafish: Possible involvement of GABAergic and serotonergic pathways
por: Adongo, Donatus Wewura, et al.
Publicado: (2023)

Randomized controlled trial assessing the effectiveness of midazolam premedication as an anxiolytic, analgesic, sedative, and hemodynamic stabilizer
por: Jeon, Soeun, et al.
Publicado: (2018)

ANXIOLYTIC - LIKE PROPERTIES OF Hallea ciliata IN MICE
por: Stephanie, Njapdounke Kameni Jacqueline, et al.
Publicado: (2016)

Disulfiram Produces Potent Anxiolytic-Like Effects Without Benzodiazepine Anxiolytics-Related Adverse Effects in Mice
por: Saitoh, Akiyoshi, et al.
Publicado: (2022)

Anxiolytic and anti-stress effects of acute administration of acetyl-L-carnitine in zebrafish
por: Pancotto, Lais, et al.
Publicado: (2018)

Zebrafish as a Useful Tool in the Research of Natural Products With Potential Anxiolytic Effects
por: Cueto-Escobedo, Jonathan, et al.
Publicado: (2022)

Diazepam causes sedative rather than anxiolytic effects in C57BL/6J mice
por: Pádua-Reis, Marina, et al.
Publicado: (2021)

Reversion of in vivo fibrogenesis by novel chromone scaffolds
por: Kim, Han-Soo, et al.
Publicado: (2019)

Anxiolytic-Like and Antinociceptive Effects of 2(S)-Neoponcirin in Mice
por: Cassani, Julia, et al.
Publicado: (2013)

Chemical composition of the essential oil from Kelussia odoratissima Mozaff. and the evaluation of its sedative and anxiolytic effects in mice
por: Rabbani, Mohammed, et al.
Publicado: (2011)

A Valepotriate Fraction of Valeriana glechomifolia Shows Sedative and Anxiolytic Properties and Impairs Recognition But Not Aversive Memory in Mice
por: Maurmann, Natasha, et al.
Publicado: (2011)

Antinociceptive and Anxiolytic and Sedative Effects of Methanol Extract of Anisomeles indica: An Experimental Assessment in Mice and Computer Aided Models
por: Uddin, Md. Josim, et al.
Publicado: (2018)

The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative–hypnotic, antistress, anxiolytic, and cognitive effects
por: dela Peña, Irene Joy I., et al.
Publicado: (2017)

The Use of Antidepressants, Anxiolytics, Sedatives and Hypnotics in Europe: Focusing on Mental Health Care in Portugal and Prescribing in Older Patients
por: Estrela, Marta, et al.
Publicado: (2020)

Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish
por: Hussain, Akhlaq, et al.
Publicado: (2020)

Chromon-3-aldehyde derivatives restore mitochondrial function in rat cerebral ischemia
por: Pozdnyakov, Dmitry I., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4ksh0ba6rdku9oi0i7ls3pquat