Cargando…

The Function and Therapeutic Implications of TNF Signaling in MDSCs

Myeloid-derived suppressor cells (MDSCs) are a group of immature and heterogeneous myeloid cells with immunosuppressive functions. MDSCs play important roles in the pathogenesis of cancer, chronic inflammatory diseases, and many autoimmune disorders. The accumulation and activation of MDSCs can be r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Kun, Yu, Chengxin, Jiao, Liping, Miao, Kun, Ni, Li, Rao, Xiaoquan, Zhou, Ling, Zhao, Chunxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687347/ https://www.ncbi.nlm.nih.gov/pubmed/36358977 http://dx.doi.org/10.3390/biom12111627

Ejemplares similares

mTOR Signaling Regulates the Development and Therapeutic Efficacy of PMN-MDSCs in Acute GVHD
por: Li, Xiaoqing, et al.
Publicado: (2021)

MDSCs in breast cancer: an important enabler of tumor progression and an emerging therapeutic target
por: Liu, Haoyu, et al.
Publicado: (2023)

The Effect of Immunosuppressive Drugs on MDSCs in Transplantation
por: Yang, Fan, et al.
Publicado: (2018)

Mechanisms and Therapeutic Strategies of Viral Myocarditis Targeting Autophagy
por: Yu, Kun, et al.
Publicado: (2022)

Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
por: Yang, Sujuan, et al.
Publicado: (2018)

Mesenchymal Stem Cell Enhances the Function of MDSCs in Experimental Sjögren Syndrome
por: Tian, Jie, et al.
Publicado: (2020)

Targeting MDSCs enhance therapeutic vaccination responses against lung cancer
por: Srivastava, Minu K., et al.
Publicado: (2012)

Targeting the MDSCs of Tumors In Situ With Inhibitors of the MAPK Signaling Pathway to Promote Tumor Regression
por: Yu, Jiayun, et al.
Publicado: (2021)

MDSCs participate in the pathogenesis of diffuse pulmonary hemorrhage in murine lupus through mTOR-FoxO1 signaling
por: Tan, Liping, et al.
Publicado: (2022)

Immunotherapy of targeting MDSCs in tumor microenvironment
por: Sui, Hongshu, et al.
Publicado: (2022)

New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs
por: Lakshmanachetty, Senthilnath, et al.
Publicado: (2021)

Immunosuppressive MDSCs induced by TLR signaling during infection and role in resolution of inflammation
por: Ray, Anuradha, et al.
Publicado: (2013)

Immunostimulatory functions of adoptively transferred MDSCs in experimental blunt chest trauma
por: Kustermann, Monika, et al.
Publicado: (2019)

Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis
por: Xue, Yaxian, et al.
Publicado: (2019)

G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence
por: Sun, Shu-Ning, et al.
Publicado: (2021)

Catechins and antitumor immunity: Not MDSC’s cup of tea
por: Santilli, Giorgia, et al.
Publicado: (2013)

Improving cancer immunotherapy by targeting the STATe of MDSCs
por: de Haas, Nienke, et al.
Publicado: (2016)

Connections between Metabolism and Epigenetic Modification in MDSCs
por: Dai, Haiyan, et al.
Publicado: (2020)

The Engagement Between MDSCs and Metastases: Partners in Crime
por: Trovato, Rosalinda, et al.
Publicado: (2020)

Myeloid-Derived Suppressor Cells (MDSCs) in Haematology
por: Bizymi, Nikoleta, et al.
Publicado: (2021)

Activation of VIP signaling enhances immunosuppressive effect of MDSCs on CMV-induced adaptive immunity
por: Forghani, Parvin, et al.
Publicado: (2017)

MicroRNAs/LncRNAs Modulate MDSCs in Tumor Microenvironment
por: Liu, Xiaocui, et al.
Publicado: (2022)

Correction to: Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis
por: Xue, Yaxian, et al.
Publicado: (2022)

Editorial: The Role of TNF-TNFR2 Signal in Immunosuppressive Cells and Its Therapeutic Implications
por: Chen, Xin, et al.
Publicado: (2019)

Characteristics of “Tip-DCs and MDSCs” and Their Potential Role in Leishmaniasis
por: Schmid, Maximilian, et al.
Publicado: (2012)

New roles of Rb1 in expansion of MDSCs in cancer
por: Youn, Je-In, et al.
Publicado: (2013)

Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation
por: Diallo, Katy, et al.
Publicado: (2021)

Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model
por: Chang, Chun-Hsiang, et al.
Publicado: (2023)

The paradoxical role of MDSCs in inflammatory bowel diseases: From bench to bedside
por: Zhao, Fan, et al.
Publicado: (2022)

Immunotherapy Targeting Myeloid-Derived Suppressor Cells (MDSCs) in Tumor Microenvironment
por: Gao, Xidan, et al.
Publicado: (2021)

Bone marrow cells are differentiated into MDSCs by BCC‐Ex through down‐regulating the expression of CXCR4 and activating STAT3 signalling pathway
por: Liu, Quan‐Wen, et al.
Publicado: (2021)

Dual negative roles of C/EBPα in the expansion and pro-tumor functions of MDSCs
por: Mackert, John R., et al.
Publicado: (2017)

Connecting METTL3 and intratumoural CD33(+) MDSCs in predicting clinical outcome in cervical cancer
por: Ni, Huan-he, et al.
Publicado: (2020)

PReS-FINAL-2336: Induction of MDSCS in Muckle-Wells syndrome
por: Rieber, N, et al.
Publicado: (2013)

MDSCs: Key Criminals of Tumor Pre-metastatic Niche Formation
por: Wang, Yungang, et al.
Publicado: (2019)

Polymorphonuclear MDSCs are enriched in the stroma and expanded in metastases of prostate cancer
por: Wen, Jiling, et al.
Publicado: (2020)

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
por: McCoy, Melissa K, et al.
Publicado: (2008)

Monocytic MDSCs homing to thymus contribute to age-related CD8(+) T cell tolerance of HBV
por: Fang, Zhong, et al.
Publicado: (2022)

LncRNA MALAT1 negatively regulates MDSCs in patients with lung cancer
por: Zhou, Qinfeng, et al.
Publicado: (2018)

Editorial: The role of TNF-TNFR2 signal in immunosuppressive cells and its therapeutic implications, volume II
por: Chen, Xin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8jgp1f74mt5f6pqse2om9diaiq