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Changes in the Fecal Metabolome Accompany an Increase in Aberrant Crypt Foci in the Colon of C57BL/6 Mice Fed with a High-Fat Diet
High-fat diet (HFD)-induced obesity is a risk factor for colon cancer. Our previous data show that compared to an AIN-93 diet (AIN), a HFD promotes azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) formation and microbial dysbiosis in C57BL/6 mice. To explore the underlying metabolic basi...
Autores principales: | Zeng, Huawei, Safratowich, Bryan D., Cheng, Wen-Hsing, Magnuson, Andrew D., Picklo, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687353/ https://www.ncbi.nlm.nih.gov/pubmed/36428460 http://dx.doi.org/10.3390/biomedicines10112891 |
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