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Changes in the Fecal Metabolome Accompany an Increase in Aberrant Crypt Foci in the Colon of C57BL/6 Mice Fed with a High-Fat Diet

High-fat diet (HFD)-induced obesity is a risk factor for colon cancer. Our previous data show that compared to an AIN-93 diet (AIN), a HFD promotes azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) formation and microbial dysbiosis in C57BL/6 mice. To explore the underlying metabolic basi...

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Detalles Bibliográficos
Autores principales: Zeng, Huawei, Safratowich, Bryan D., Cheng, Wen-Hsing, Magnuson, Andrew D., Picklo, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687353/
https://www.ncbi.nlm.nih.gov/pubmed/36428460
http://dx.doi.org/10.3390/biomedicines10112891

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