The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation

Finasteride (Fin) causes androgen imbalance by inhibiting the conversion of testosterone (T) to its more active metabolite, dihydrotestosterone (DHT). Androgen receptors (AR) are present (e.g., in hepatocytes), which have well-developed endoplasmic reticulum (ERet). Cellular protein quality control...

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Detalles Bibliográficos
Autores principales: Rzeszotek, Sylwia, Kolasa, Agnieszka, Pilutin, Anna, Misiakiewicz-Has, Kamila, Sielatycka, Katarzyna, Wiszniewska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687381/
https://www.ncbi.nlm.nih.gov/pubmed/36359245
http://dx.doi.org/10.3390/biomedicines10112725

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