Modeling Calcium Cycling in the Heart: Progress, Pitfalls, and Challenges

Intracellular calcium (Ca) cycling in the heart plays key roles in excitation–contraction coupling and arrhythmogenesis. In cardiac myocytes, the Ca release channels, i.e., the ryanodine receptors (RyRs), are clustered in the sarcoplasmic reticulum membrane, forming Ca release units (CRUs). The RyRs...

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Detalles Bibliográficos
Autores principales: Qu, Zhilin, Yan, Dasen, Song, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687412/
https://www.ncbi.nlm.nih.gov/pubmed/36421700
http://dx.doi.org/10.3390/biom12111686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687412/
https://www.ncbi.nlm.nih.gov/pubmed/36421700
http://dx.doi.org/10.3390/biom12111686

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