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Global Regulator AdpA_1075 Regulates Morphological Differentiation and Ansamitocin Production in Actinosynnema pretiosum subsp. auranticum

Actinosynnema pretiosum is a well-known producer of maytansinoid antibiotic ansamitocin P-3 (AP-3). Growth of A. pretiosum in submerged culture was characterized by the formation of complex mycelial particles strongly affecting AP-3 production. However, the genetic determinants involved in mycelial...

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Detalles Bibliográficos
Autores principales: Guo, Siyu, Leng, Tingting, Sun, Xueyuan, Zheng, Jiawei, Li, Ruihua, Chen, Jun, Hu, Fengxian, Liu, Feng, Hua, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687425/
https://www.ncbi.nlm.nih.gov/pubmed/36421120
http://dx.doi.org/10.3390/bioengineering9110719