Essential Role of Histidine for Rapid Copper(II)-Mediated Disassembly of Neurokinin B Amyloid

Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core secretory vesicles within hypothalamic neurons. Disassembly of the amyloid is thought to require th...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayawardena, Bhawantha M., Peacey, Lorraine, Gamsjaeger, Roland, Jones, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687585/
https://www.ncbi.nlm.nih.gov/pubmed/36358935
http://dx.doi.org/10.3390/biom12111585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687585/
https://www.ncbi.nlm.nih.gov/pubmed/36358935
http://dx.doi.org/10.3390/biom12111585

Ejemplares similares