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Essential Role of Histidine for Rapid Copper(II)-Mediated Disassembly of Neurokinin B Amyloid
Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core secretory vesicles within hypothalamic neurons. Disassembly of the amyloid is thought to require th...
Autores principales: | Jayawardena, Bhawantha M., Peacey, Lorraine, Gamsjaeger, Roland, Jones, Christopher E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687585/ https://www.ncbi.nlm.nih.gov/pubmed/36358935 http://dx.doi.org/10.3390/biom12111585 |
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