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Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics

Cardiovascular system abnormalities can result in serious health complications. By using the fluid–structure interaction (FSI) procedure, a comprehensive realistic approach can be employed to accurately investigate blood flow coupled with arterial wall response. The hemodynamics was investigated in...

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Autores principales: Albadawi, Muhamed, Abuouf, Yasser, Elsagheer, Samir, Sekiguchi, Hidetoshi, Ookawara, Shinichi, Ahmed, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687628/
https://www.ncbi.nlm.nih.gov/pubmed/36421109
http://dx.doi.org/10.3390/bioengineering9110708
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author Albadawi, Muhamed
Abuouf, Yasser
Elsagheer, Samir
Sekiguchi, Hidetoshi
Ookawara, Shinichi
Ahmed, Mahmoud
author_facet Albadawi, Muhamed
Abuouf, Yasser
Elsagheer, Samir
Sekiguchi, Hidetoshi
Ookawara, Shinichi
Ahmed, Mahmoud
author_sort Albadawi, Muhamed
collection PubMed
description Cardiovascular system abnormalities can result in serious health complications. By using the fluid–structure interaction (FSI) procedure, a comprehensive realistic approach can be employed to accurately investigate blood flow coupled with arterial wall response. The hemodynamics was investigated in both the coronary and carotid arteries based on the arterial wall response. The hemodynamics was estimated based on the numerical simulation of a comprehensive three-dimensional non-Newtonian blood flow model in elastic and rigid arteries. For stenotic right coronary artery (RCA), it was found that the maximum value of wall shear stress (WSS) for the FSI case is higher than the rigid wall. On the other hand, for the stenotic carotid artery (CA), it was found that the maximum value of WSS for the FSI case is lower than the rigid wall. Moreover, at the peak systole of the cardiac cycle (0.38 s), the maximum percentage of arterial wall deformation was found to be 1.9%. On the other hand, for the stenotic carotid artery, the maximum percentage of arterial wall deformation was found to be 0.46%. A comparison between FSI results and those obtained by rigid wall arteries is carried out. Findings indicate slight differences in results for large-diameter arteries such as the carotid artery. Accordingly, the rigid wall assumption is plausible in flow modeling for relatively large diameters such as the carotid artery. Additionally, the FSI approach is essential in flow modeling in small diameters.
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spelling pubmed-96876282022-11-25 Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics Albadawi, Muhamed Abuouf, Yasser Elsagheer, Samir Sekiguchi, Hidetoshi Ookawara, Shinichi Ahmed, Mahmoud Bioengineering (Basel) Article Cardiovascular system abnormalities can result in serious health complications. By using the fluid–structure interaction (FSI) procedure, a comprehensive realistic approach can be employed to accurately investigate blood flow coupled with arterial wall response. The hemodynamics was investigated in both the coronary and carotid arteries based on the arterial wall response. The hemodynamics was estimated based on the numerical simulation of a comprehensive three-dimensional non-Newtonian blood flow model in elastic and rigid arteries. For stenotic right coronary artery (RCA), it was found that the maximum value of wall shear stress (WSS) for the FSI case is higher than the rigid wall. On the other hand, for the stenotic carotid artery (CA), it was found that the maximum value of WSS for the FSI case is lower than the rigid wall. Moreover, at the peak systole of the cardiac cycle (0.38 s), the maximum percentage of arterial wall deformation was found to be 1.9%. On the other hand, for the stenotic carotid artery, the maximum percentage of arterial wall deformation was found to be 0.46%. A comparison between FSI results and those obtained by rigid wall arteries is carried out. Findings indicate slight differences in results for large-diameter arteries such as the carotid artery. Accordingly, the rigid wall assumption is plausible in flow modeling for relatively large diameters such as the carotid artery. Additionally, the FSI approach is essential in flow modeling in small diameters. MDPI 2022-11-18 /pmc/articles/PMC9687628/ /pubmed/36421109 http://dx.doi.org/10.3390/bioengineering9110708 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Albadawi, Muhamed
Abuouf, Yasser
Elsagheer, Samir
Sekiguchi, Hidetoshi
Ookawara, Shinichi
Ahmed, Mahmoud
Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title_full Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title_fullStr Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title_full_unstemmed Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title_short Influence of Rigid–Elastic Artery Wall of Carotid and Coronary Stenosis on Hemodynamics
title_sort influence of rigid–elastic artery wall of carotid and coronary stenosis on hemodynamics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687628/
https://www.ncbi.nlm.nih.gov/pubmed/36421109
http://dx.doi.org/10.3390/bioengineering9110708
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