Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not

Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical syst...

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Autores principales: Argirò, Alessia, Del Franco, Annamaria, Mazzoni, Carlotta, Allinovi, Marco, Tomberli, Alessia, Tarquini, Roberto, Di Mario, Carlo, Perfetto, Federico, Cappelli, Francesco, Zampieri, Mattia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687719/
https://www.ncbi.nlm.nih.gov/pubmed/36359408
http://dx.doi.org/10.3390/biomedicines10112888
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author Argirò, Alessia
Del Franco, Annamaria
Mazzoni, Carlotta
Allinovi, Marco
Tomberli, Alessia
Tarquini, Roberto
Di Mario, Carlo
Perfetto, Federico
Cappelli, Francesco
Zampieri, Mattia
author_facet Argirò, Alessia
Del Franco, Annamaria
Mazzoni, Carlotta
Allinovi, Marco
Tomberli, Alessia
Tarquini, Roberto
Di Mario, Carlo
Perfetto, Federico
Cappelli, Francesco
Zampieri, Mattia
author_sort Argirò, Alessia
collection PubMed
description Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical system deserve more attention, as well as the study of the underlying molecular mechanisms. This is an issue of considerable interest, given the conflicting data on the effectiveness of conventional antiarrhythmic strategies. Therefore, this review aims at summarizing the arrhythmic burden related to CA and the available evidence on antiarrhythmic treatment in this population.
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spelling pubmed-96877192022-11-25 Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not Argirò, Alessia Del Franco, Annamaria Mazzoni, Carlotta Allinovi, Marco Tomberli, Alessia Tarquini, Roberto Di Mario, Carlo Perfetto, Federico Cappelli, Francesco Zampieri, Mattia Biomedicines Review Cardiac amyloidosis (CA), caused by the deposition of insoluble amyloid fibrils, impairs different cardiac structures, altering not only left ventricle (LV) systo-diastolic function but also atrial function and the conduction system. The consequences of the involvement of the cardiac electrical system deserve more attention, as well as the study of the underlying molecular mechanisms. This is an issue of considerable interest, given the conflicting data on the effectiveness of conventional antiarrhythmic strategies. Therefore, this review aims at summarizing the arrhythmic burden related to CA and the available evidence on antiarrhythmic treatment in this population. MDPI 2022-11-10 /pmc/articles/PMC9687719/ /pubmed/36359408 http://dx.doi.org/10.3390/biomedicines10112888 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Argirò, Alessia
Del Franco, Annamaria
Mazzoni, Carlotta
Allinovi, Marco
Tomberli, Alessia
Tarquini, Roberto
Di Mario, Carlo
Perfetto, Federico
Cappelli, Francesco
Zampieri, Mattia
Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title_full Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title_fullStr Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title_full_unstemmed Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title_short Arrhythmic Burden in Cardiac Amyloidosis: What We Know and What We Do Not
title_sort arrhythmic burden in cardiac amyloidosis: what we know and what we do not
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687719/
https://www.ncbi.nlm.nih.gov/pubmed/36359408
http://dx.doi.org/10.3390/biomedicines10112888
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