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Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates

Most neurodegenerative diseases have the characteristics of protein folding disorders, i.e., they cause lesions to appear in vulnerable regions of the nervous system, corresponding to protein aggregates that progressively spread through the neuronal network as the symptoms progress. Alzheimer’s dise...

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Detalles Bibliográficos
Autores principales: Papadopoulos, Nicolas, Suelves, Nuria, Perrin, Florian, Vadukul, Devkee M., Vrancx, Céline, Constantinescu, Stefan N., Kienlen-Campard, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687742/
https://www.ncbi.nlm.nih.gov/pubmed/36359274
http://dx.doi.org/10.3390/biomedicines10112753