Cargando…

The Human Myofibroblast Marker Xylosyltransferase-I: A New Indicator for Macrophage Polarization

Chronic inflammation and excessive synthesis of extracellular matrix components, such as proteoglycans (PG), by fibroblast- or macrophage-derived myofibroblasts are the hallmarks of fibrotic diseases, including systemic sclerosis (SSc). Human xylosyltransferase-I (XT-I), which is encoded by the gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ly, Thanh-Diep, Wolny, Monika, Lindenkamp, Christopher, Birschmann, Ingvild, Hendig, Doris, Knabbe, Cornelius, Faust-Hinse, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687871/ https://www.ncbi.nlm.nih.gov/pubmed/36359389 http://dx.doi.org/10.3390/biomedicines10112869

Ejemplares similares

The Impact of Inflammatory Stimuli on Xylosyltransferase-I Regulation in Primary Human Dermal Fibroblasts
por: Ly, Thanh-Diep, et al.
Publicado: (2022)

Human Xylosyltransferase I—An Important Linker between Acute Senescence and Fibrogenesis
por: Schmidt, Vanessa, et al.
Publicado: (2023)

microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
por: Riedel, Lara, et al.
Publicado: (2018)

First Characterization of Human Dermal Fibroblasts Showing a Decreased Xylosyltransferase-I Expression Induced by the CRISPR/Cas9 System
por: Fischer, Bastian, et al.
Publicado: (2022)

First description of the complete human xylosyltransferase-I promoter region
por: Faust, Isabel, et al.
Publicado: (2014)

Evidence of Long-Lasting Humoral and Cellular Immunity against SARS-CoV-2 Even in Elderly COVID-19 Convalescents Showing a Mild to Moderate Disease Progression
por: Fischer, Bastian, et al.
Publicado: (2021)

Human xylosyltransferases – mediators of arthrofibrosis? New pathomechanistic insights into arthrofibrotic remodeling after knee replacement therapy
por: Faust, Isabel, et al.
Publicado: (2015)

Understanding of arthrofibrosis: New explorative insights into extracellular matrix remodeling of synovial fibroblasts
por: Ly, Thanh-Diep, et al.
Publicado: (2023)

Statins as a Therapeutic Approach for the Treatment of Pseudoxanthoma Elasticum Patients: Evaluation of the Spectrum Efficacy of Atorvastatin In Vitro
por: Tiemann, Janina, et al.
Publicado: (2021)

Linking ABCC6 Deficiency in Primary Human Dermal Fibroblasts of PXE Patients to p21-Mediated Premature Cellular Senescence and the Development of a Proinflammatory Secretory Phenotype
por: Tiemann, Janina, et al.
Publicado: (2020)

Identification of Putative Non-Substrate-Based XT-I Inhibitors by Natural Product Library Screening
por: Ly, Thanh-Diep, et al.
Publicado: (2020)

Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
por: Ly, Thanh-Diep, et al.
Publicado: (2020)

Targeting ABCC6 in Mesenchymal Stem Cells: Impairment of Mature Adipocyte Lipid Homeostasis
por: Plümers, Ricarda, et al.
Publicado: (2022)

Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum
por: Plümers, Ricarda, et al.
Publicado: (2023)

UPLC-MRM Mass Spectrometry Method for Measurement of the Coagulation Inhibitors Dabigatran and Rivaroxaban in Human Plasma and Its Comparison with Functional Assays
por: Kuhn, Joachim, et al.
Publicado: (2015)

Changes in the Proteome of Platelets from Patients with Critical Progression of COVID-19
por: Wolny, Monika, et al.
Publicado: (2023)

The Activation of JAK/STAT3 Signaling and the Complement System Modulate Inflammation in the Primary Human Dermal Fibroblasts of PXE Patients
por: Lindenkamp, Christopher, et al.
Publicado: (2023)

Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients
por: Tiemann, Janina, et al.
Publicado: (2019)

ABCC6- a new player in cellular cholesterol and lipoprotein metabolism?
por: Kuzaj, Patricia, et al.
Publicado: (2014)

New insights into the pathogenesis of pseudoxanthoma elasticum and related soft tissue calcification disorders by identifying genetic interactions and modifiers
por: Hendig, Doris, et al.
Publicado: (2013)

Pathobiochemistry of arthrofibrotic remodeling
por: Faust, Isabel, et al.
Publicado: (2017)

Strain-dependent interactions of Streptococcus gallolyticus subsp. gallolyticus with human blood cells
por: Grimm, Imke, et al.
Publicado: (2017)

Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls
por: Kuzaj, Patricia, et al.
Publicado: (2014)

Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues
por: Ibold, Bettina, et al.
Publicado: (2019)

Retrospective study shows that early administration of convalescent plasma in hospitalized COVID‐19 patients may have a positive effect on disease progression
por: Birschmann, Ingvild, et al.
Publicado: (2022)

Humoral and cellular immune response levels at a 1-year follow-up after mild COVID-19
por: Flieder, Tobias, et al.
Publicado: (2022)

Retrospective analysis of 426 donors of a convalescent collective after mild COVID-19
por: Flieder, Tobias, et al.
Publicado: (2021)

Expression of xylosyltransferases I and II and their role in the pathogenesis of arthrofibrosis
por: Bernstein, Anke, et al.
Publicado: (2020)

Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1
por: Briggs, David C., et al.
Publicado: (2018)

Pharmacokinetics and Biologic Activity of Apixaban in Healthy Dogs
por: Herrera, Noelle D., et al.
Publicado: (2021)

Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice
por: Ibold, Bettina, et al.
Publicado: (2021)

Effect of Xylosyltransferase-I Silencing on Implanting Growth of Salivary Pleomorphic Adenoma
por: Ren, Guiyun, et al.
Publicado: (2018)

Potential Transmission Pathways of Streptococcus gallolyticus subsp. gallolyticus
por: Dumke, Jessika, et al.
Publicado: (2015)

Incidence of elevated lipoprotein (a) levels in a large cohort of patients with cardiovascular disease
por: van Buuren, Frank, et al.
Publicado: (2017)

The Sysmex CS-5100 coagulation analyzer offers comparable analytical performance and excellent throughput capabilities
por: Flieder, T., et al.
Publicado: (2016)

Macrophage polarization induces endothelium-to-myofibroblast transition in chronic allograft dysfunction
por: Gui, Zeping, et al.
Publicado: (2023)

Molecular cloning and characterization of a novel tomato xylosyltransferase specific for gentisic acid
por: Tárraga, Susana, et al.
Publicado: (2010)

Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis
por: Venkatesan, Narayanan, et al.
Publicado: (2012)

Complete genome and comparative analysis of Streptococcus gallolyticus subsp. gallolyticus, an emerging pathogen of infective endocarditis
por: Hinse, Dennis, et al.
Publicado: (2011)

Serum Xylosyltransferase Activity in Diabetic Patients as a Possible Marker of Reduced Proteoglycan Biosynthesis
por: Götting, Christian, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_9qh3gqsovocj79kv3gepsjk6jo