Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder

Chronic cocaine use leads to adaptations in stress biology and in neuroactive steroid system. These adaptations are associated with high cocaine craving and increased relapse risk. This study tested whether potentiation of the neuroactive steroid system with the precursor pregnenolone (PREG) affects...

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Detalles Bibliográficos
Autores principales: Milivojevic, Verica, Charron, Lily, Fogelman, Nia, Hermes, Gretchen, Sinha, Rajita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687893/
https://www.ncbi.nlm.nih.gov/pubmed/36358943
http://dx.doi.org/10.3390/biom12111593

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