Osteoarthritis Pain in Old Mice Aggravates Neuroinflammation and Frailty: The Positive Effect of Morphine Treatment

Knee osteoarthritis is a common cause of pain and disability in old subjects. Pain may predispose to the development of frailty. Studies on mechanisms underlying pain in osteoarthritis models during aging are lacking. In this work, we used the monosodium iodoacetate model of osteoarthritis in adult...

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Detalles Bibliográficos
Autores principales: Amodeo, Giada, Franchi, Silvia, Galimberti, Giulia, Comi, Laura, D’Agnelli, Simona, Baciarello, Marco, Bignami, Elena Giovanna, Sacerdote, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687902/
https://www.ncbi.nlm.nih.gov/pubmed/36359375
http://dx.doi.org/10.3390/biomedicines10112847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687902/
https://www.ncbi.nlm.nih.gov/pubmed/36359375
http://dx.doi.org/10.3390/biomedicines10112847

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