Cargando…

Placenta-Targeted Nanoparticles Loaded with PFKFB3 Overexpression Plasmids Enhance Angiogenesis and Placental Function

Placental angiogenesis disorder and placental dysplasia are important causes of many pregnancy complications. Due to safety and economic benefits, effective treatment strategies are currently limited. PFKFB3 is a key regulator of glycolysis that controls angiogenesis through a metabolic pathway inde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qi, Liu, Xiaoxia, Liu, Weifang, Zhang, Yang, Liu, Wen, Wu, Mengying, Chen, Zhirui, Zhao, Yin, Zou, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687907/ https://www.ncbi.nlm.nih.gov/pubmed/36354563 http://dx.doi.org/10.3390/bioengineering9110652

Ejemplares similares

MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia
por: Li, Qi, et al.
Publicado: (2021)

PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells
por: Zhang, Yang, et al.
Publicado: (2022)

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia
por: Zhang, Yang, et al.
Publicado: (2021)

Significance of Placental Mesenchymal Stem Cell in Placenta Development and Implications for Preeclampsia
por: Zhang, Yang, et al.
Publicado: (2022)

PFKFB3 promotes proliferation, migration and angiogenesis in nasopharyngeal carcinoma
por: Gu, Miao, et al.
Publicado: (2017)

PFKFB3: A Potential Key to Ocular Angiogenesis
por: Zhou, Zi-Yi, et al.
Publicado: (2021)

TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia
por: Zhong, Yanqi, et al.
Publicado: (2022)

The influence of PFK-II overexpression on neuroblastoma patients’ survival may be dependent on the particular isoenzyme expressed, PFKFB3 or PFKFB4
por: Trojan, Sonia E., et al.
Publicado: (2019)

KDM2A Targets PFKFB3 for Ubiquitylation to Inhibit the Proliferation and Angiogenesis of Multiple Myeloma Cells
por: Liu, Xinling, et al.
Publicado: (2021)

Overexpression of PFKFB3 promotes cell glycolysis and proliferation in renal cell carcinoma
por: Li, Jun, et al.
Publicado: (2022)

A Potential Oncogenic Role for PFKFB3 Overexpression in Gastric Cancer Progression
por: Lei, Lan, et al.
Publicado: (2021)

The PFKFB3 Inhibitor AZ67 Inhibits Angiogenesis Independently of Glycolysis Inhibition
por: Emini Veseli, Besa, et al.
Publicado: (2021)

Roles of PFKFB3 in cancer
por: Shi, Linlin, et al.
Publicado: (2017)

Role of PFKFB3-driven glycolysis in sepsis
por: Xiao, Min, et al.
Publicado: (2023)

P880: OVEREXPRESSION OF PFKFB4 PROMOTES ADAPTATION TO HYPOXIC MICROENVIRONMENT IN MULTIPLE MYELOMA
por: Yang, J., et al.
Publicado: (2022)

PFKFB4 promotes angiogenesis via IL-6/STAT5A/P-STAT5 signaling in breast cancer
por: Li, Dan, et al.
Publicado: (2022)

Ultrasonographic Prediction of Placental Invasion in Placenta Previa by Placenta Accreta Index
por: Hasegawa, Keita, et al.
Publicado: (2023)

Abnormal angiogenesis of placenta in progranulin-deficient mice
por: Xu, Bairuo, et al.
Publicado: (2020)

The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue
por: Li, Ximing, et al.
Publicado: (2020)

Management of the Placenta in the Third or Placental Stage of Labor
por: Comstock, T. Griswold
Publicado: (1888)

Therapeutic targeting of PFKFB3 and PFKFB4 in multiple myeloma cells under hypoxic conditions
por: Okabe, Seiichi, et al.
Publicado: (2022)

Reactive Oxygen Species are Essential for Placental Angiogenesis During Early Gestation
por: Yang, Yike, et al.
Publicado: (2022)

PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance
por: Feng, Chenchen, et al.
Publicado: (2021)

Netrins and Their Roles in Placental Angiogenesis
por: Dakouane-Giudicelli, Mbarka, et al.
Publicado: (2014)

Normal and Pathological Placental Angiogenesis
por: Bardin, Nathalie, et al.
Publicado: (2015)

UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation
por: Sreedhar, Annapoorna, et al.
Publicado: (2017)

Conditioned medium from primary cytotrophoblasts, primary placenta-derived mesenchymal stem cells, or sub-cultured placental tissue promoted HUVEC angiogenesis in vitro
por: Ma, Haiying, et al.
Publicado: (2021)

Correction to: PFKFB4 is overexpressed in clear-cell renal cell carcinoma promoting pentose phosphate pathway that mediates Sunitinib resistance
por: Feng, Chenchen, et al.
Publicado: (2021)

The placental transcriptome of the first-trimester placenta is affected by in vitro fertilization and embryo transfer
por: Zhao, Liang, et al.
Publicado: (2019)

Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation
por: Cheng, Xiao, et al.
Publicado: (2023)

Therapeutic Angiogenesis Using HGF Plasmid
por: Sanada, Fumihiro, et al.
Publicado: (2020)

Intrauterine growth restriction and placental angiogenesis
por: Barut, Figen, et al.
Publicado: (2010)

Estrogens Regulate Placental Angiogenesis in Horses
por: Haneda, Shingo, et al.
Publicado: (2021)

Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis
por: Chen, Weimou, et al.
Publicado: (2021)

Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss
por: Wang, Jia, et al.
Publicado: (2019)

PFKFB4 Overexpression Facilitates Proliferation by Promoting the G1/S Transition and Is Associated with a Poor Prognosis in Triple-Negative Breast Cancer
por: Cai, Yu-Chen, et al.
Publicado: (2021)

Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets
por: Kotowski, Krzysztof, et al.
Publicado: (2021)

Overexpressed HO-1 is associated with reduced STAT3 activation in preeclampsia placenta and inhibits STAT3 phosphorylation in placental JEG-3 cells under hypoxia
por: Qu, Hong-Mei, et al.
Publicado: (2016)

Effect of site of placentation on pregnancy outcomes in patients with placenta previa
por: Jing, Lin, et al.
Publicado: (2018)

Serine Hydrolases in Lipid Homeostasis of the Placenta-Targets for Placental Function?
por: Berger, Natascha, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9vvd9crer99t3o7vg89cm0m2bj