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Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants

Organ fibrosis, particularly of the lungs, causes significant morbidity and mortality. Effective treatments are needed to reduce the health burden. A fragment of the carboxyl-terminal end of collagen XVIII/endostatin reduces skin and lung fibrosis. This fragment was modified to facilitate its produc...

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Detalles Bibliográficos
Autores principales: Mlakar, Logan, Garrett, Sara M., Watanabe, Tomoya, Sanderson, Matthew, Nishimoto, Tetsuya, Heywood, Jonathan, Helke, Kristi L., Pilewski, Joseph M., Herzog, Erica L., Feghali-Bostwick, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687961/
https://www.ncbi.nlm.nih.gov/pubmed/36359382
http://dx.doi.org/10.3390/biomedicines10112861