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Predicting Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) of HRAS Gene and In Silico Evaluation of Their Structural and Functional Consequences towards Diagnosis and Prognosis of Cancer

SIMPLE SUMMARY: The HRAS gene has been reported to cause cancer, and identifying alleles that could potentially predispose one to cancer could lead to early diagnosis and better prognosis. Here for the first time, we conducted a machine-learning approach to identify high-risk predictive alleles of t...

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Detalles Bibliográficos
Autores principales:	Chai, Chuan-Yu, Maran, Sathiya, Thew, Hin-Yee, Tan, Yong-Chiang, Rahman, Nik Mohd Afizan Nik Abd, Cheng, Wan-Hee, Lai, Kok-Song, Loh, Jiun-Yan, Yap, Wai-Sum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688001/ https://www.ncbi.nlm.nih.gov/pubmed/36358305 http://dx.doi.org/10.3390/biology11111604

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