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USP7 Inhibitors in Cancer Immunotherapy: Current Status and Perspective

SIMPLE SUMMARY: Elevated levels of ubiquitin-specific protease 7 (USP7) are associated with poor survival in many cancers. This protein impairs the balance of various cellular proteins and regulates the anti-tumor immune response. Its inhibition affects regulatory T cells and tumor-associated macrop...

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Detalles Bibliográficos
Autores principales: Korenev, Georgiy, Yakukhnov, Sergey, Druk, Anastasia, Golovina, Anastasia, Chasov, Vitaly, Mirgayazova, Regina, Ivanov, Roman, Bulatov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688046/
https://www.ncbi.nlm.nih.gov/pubmed/36428632
http://dx.doi.org/10.3390/cancers14225539

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