N6-Methyladenosine Modification of CIRCKRT17 Initiated by METTL3 Promotes Osimertinib Resistance of Lung Adenocarcinoma by EIF4A3 to Enhance YAP1 Stability

SIMPLE SUMMARY: Circular RNA KRT17 (circKRT17) is elevated in osimertinib-resistant lung cancer cells by a circRNA microarray analysis. However, the functional role of circKRT17 in the osimertinib resistance of lung adenocarcinoma (LUAD) remains undetermined. Herein, we found that circKRT17 and METT...

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Detalles Bibliográficos
Autores principales: Ji, Ying, Zhao, Qing, Feng, Wei, Peng, Yue, Hu, Bin, Chen, Qirui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688051/
https://www.ncbi.nlm.nih.gov/pubmed/36428672
http://dx.doi.org/10.3390/cancers14225582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688051/
https://www.ncbi.nlm.nih.gov/pubmed/36428672
http://dx.doi.org/10.3390/cancers14225582

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