Culture of Cancer Cells at Physiological Oxygen Levels Affects Gene Expression in a Cell-Type Specific Manner

Standard cell culture is routinely performed at supraphysiological oxygen levels (~18% O(2)). Conversely, O(2) levels in most mammalian tissues range from 1–6% (physioxia). Such hyperoxic conditions in cell culture can alter reactive oxygen species (ROS) production, metabolism, mitochondrial network...

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Detalles Bibliográficos
Autores principales: Alva, Ricardo, Moradi, Fereshteh, Liang, Ping, Stuart, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688152/
https://www.ncbi.nlm.nih.gov/pubmed/36421698
http://dx.doi.org/10.3390/biom12111684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688152/
https://www.ncbi.nlm.nih.gov/pubmed/36421698
http://dx.doi.org/10.3390/biom12111684

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