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Culture of Cancer Cells at Physiological Oxygen Levels Affects Gene Expression in a Cell-Type Specific Manner
Standard cell culture is routinely performed at supraphysiological oxygen levels (~18% O(2)). Conversely, O(2) levels in most mammalian tissues range from 1–6% (physioxia). Such hyperoxic conditions in cell culture can alter reactive oxygen species (ROS) production, metabolism, mitochondrial network...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688152/ https://www.ncbi.nlm.nih.gov/pubmed/36421698 http://dx.doi.org/10.3390/biom12111684 |