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Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders

The Hippo pathway consists of a cascade of kinases that controls the phosphorylation of the co-activators YAP/TAZ. When unphosphorylated, YAP and TAZ translocate into the nucleus, where they mainly bind to the TEAD transcription factor family and activate genes related to cell proliferation and surv...

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Detalles Bibliográficos
Autores principales: Sileo, Pasquale, Simonin, Clémence, Melnyk, Patricia, Chartier-Harlin, Marie-Christine, Cotelle, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688160/
https://www.ncbi.nlm.nih.gov/pubmed/36429058
http://dx.doi.org/10.3390/cells11223631