Cargando…

Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington’s Disease and Other Neurodegenerative Disorders

The Hippo pathway consists of a cascade of kinases that controls the phosphorylation of the co-activators YAP/TAZ. When unphosphorylated, YAP and TAZ translocate into the nucleus, where they mainly bind to the TEAD transcription factor family and activate genes related to cell proliferation and surv...

Descripción completa

Detalles Bibliográficos
Autores principales: Sileo, Pasquale, Simonin, Clémence, Melnyk, Patricia, Chartier-Harlin, Marie-Christine, Cotelle, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688160/
https://www.ncbi.nlm.nih.gov/pubmed/36429058
http://dx.doi.org/10.3390/cells11223631

Ejemplares similares