Targeting TET2 as a Therapeutic Approach for Angioimmunoblastic T Cell Lymphoma

SIMPLE SUMMARY: Recent advances in exome sequencing and comprehensive genomic studies have shed new light on the pathogenesis and mutational landscape of Angioimmunoblastic T-cell lymphoma (AITL). The essential pathogenic role of recurrent TET2, DNMT3A, IDH2, and RHOA mutations in AITL has been iden...

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Detalles Bibliográficos
Autores principales: Hu, Lina, Zhang, Xuanye, Li, Huifeng, Lin, Suxia, Zang, Shengbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688210/
https://www.ncbi.nlm.nih.gov/pubmed/36428791
http://dx.doi.org/10.3390/cancers14225699

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