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Tissue-Specific Human Extracellular Matrix Scaffolds Promote Pancreatic Tumour Progression and Chemotherapy Resistance
Over 80% of patients with pancreatic ductal adenocarcinoma (PDAC) are diagnosed at a late stage and are locally advanced or with concurrent metastases. The aggressive phenotype and relative chemo- and radiotherapeutic resistance of PDAC is thought to be mediated largely by its prominent stroma, whic...
Autores principales: | Al-Akkad, Walid, Acedo, Pilar, Vilia, Maria-Giovanna, Frenguelli, Luca, Ney, Alexander, Rodriguez-Hernandez, Irene, Labib, Peter L., Tamburrino, Domenico, Spoletini, Gabriele, Hall, Andrew R., Canestrari, Simone, Osnato, Anna, Garcia-Bernardo, Jose, Sejour, Leinal, Vassileva, Vessela, Vlachos, Ioannis S., Fusai, Giuseppe, Luong, Tu Vinh, Whittaker, Steven R., Pereira, Stephen P., Vallier, Ludovic, Pinzani, Massimo, Rombouts, Krista, Mazza, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688243/ https://www.ncbi.nlm.nih.gov/pubmed/36429078 http://dx.doi.org/10.3390/cells11223652 |
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