S-nitrosylated PARIS Leads to the Sequestration of PGC-1α into Insoluble Deposits in Parkinson’s Disease Model

Neuronal accumulation of parkin-interacting substrate (PARIS), a transcriptional repressor of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), has been observed in Parkinson’s disease (PD). Herein, we showed that PARIS can be S-nitrosylated at cysteine 265 (C265), and S...

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Detalles Bibliográficos
Autores principales: Kim, Hanna, Lee, Ji-Yeong, Park, Soo Jeong, Kwag, Eunsang, Kim, Jihye, Shin, Joo-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688248/
https://www.ncbi.nlm.nih.gov/pubmed/36429110
http://dx.doi.org/10.3390/cells11223682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688248/
https://www.ncbi.nlm.nih.gov/pubmed/36429110
http://dx.doi.org/10.3390/cells11223682

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