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Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review

This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into two large groups based on the way they create flow: passive systems (non-mechanical systems) and active (mechanical) systems. Each group is...

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Detalles Bibliográficos
Autores principales: Iakovlev, Aleksei P., Erofeev, Alexander S., Gorelkin, Petr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688261/
https://www.ncbi.nlm.nih.gov/pubmed/36354465
http://dx.doi.org/10.3390/bios12110956
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author Iakovlev, Aleksei P.
Erofeev, Alexander S.
Gorelkin, Petr V.
author_facet Iakovlev, Aleksei P.
Erofeev, Alexander S.
Gorelkin, Petr V.
author_sort Iakovlev, Aleksei P.
collection PubMed
description This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into two large groups based on the way they create flow: passive systems (non-mechanical systems) and active (mechanical) systems. Each group is presented by a number of device fabrications. We try to explain the main principles of operation, and we list advantages and disadvantages of the presented systems. Mechanical systems are considered in more detail, as they are currently an area of increased interest due to their unique precision flow control and “multitasking”. These systems are often applied as mini-laboratories, working autonomously without any additional operations, provided by humans, which is very important under complicated conditions. We also reviewed the integration of autonomous microfluidic systems with a smartphone or single-board computer when all data are retrieved and processed without using a personal computer. In addition, we discuss future trends and possible solutions for further development of this area of technology.
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spelling pubmed-96882612022-11-25 Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review Iakovlev, Aleksei P. Erofeev, Alexander S. Gorelkin, Petr V. Biosensors (Basel) Review This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into two large groups based on the way they create flow: passive systems (non-mechanical systems) and active (mechanical) systems. Each group is presented by a number of device fabrications. We try to explain the main principles of operation, and we list advantages and disadvantages of the presented systems. Mechanical systems are considered in more detail, as they are currently an area of increased interest due to their unique precision flow control and “multitasking”. These systems are often applied as mini-laboratories, working autonomously without any additional operations, provided by humans, which is very important under complicated conditions. We also reviewed the integration of autonomous microfluidic systems with a smartphone or single-board computer when all data are retrieved and processed without using a personal computer. In addition, we discuss future trends and possible solutions for further development of this area of technology. MDPI 2022-11-01 /pmc/articles/PMC9688261/ /pubmed/36354465 http://dx.doi.org/10.3390/bios12110956 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Iakovlev, Aleksei P.
Erofeev, Alexander S.
Gorelkin, Petr V.
Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title_full Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title_fullStr Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title_full_unstemmed Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title_short Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review
title_sort novel pumping methods for microfluidic devices: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688261/
https://www.ncbi.nlm.nih.gov/pubmed/36354465
http://dx.doi.org/10.3390/bios12110956
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