Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling

Castration-resistant prostate cancer (CRPC) remains an incurable and lethal malignancy. The development of new CRPC treatment strategies is strongly impeded by the scarcity of representative, scalable and transferable preclinical models of advanced, androgen receptor (AR)-driven CRPC. Here, we prese...

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Detalles Bibliográficos
Autores principales: Van Hemelryk, Annelies, Tomljanovic, Ingrid, de Ridder, Corrina M. A., Stuurman, Debra C., Teubel, Wilma J., Erkens-Schulze, Sigrun, Verhoef, Esther I., Remmers, Sebastiaan, Mahes, Amrish J., van Leenders, Geert J. L. H., van Royen, Martin E., van de Werken, Harmen J. G., Grudniewska, Magda, Jenster, Guido W., van Weerden, Wytske M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688335/
https://www.ncbi.nlm.nih.gov/pubmed/36429059
http://dx.doi.org/10.3390/cells11223632

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