Recent Trends and Advancements in the Diagnosis and Management of Gastric Cancer

SIMPLE SUMMARY: Gastric cancer is the fifth most common tumor worldwide. In the past couple of decades, there have been many advancements toward earlier detection and better treatments for this aggressive disease. There are currently many serological tests and biomarkers being investigated to allow for the non-invasive early diagnosis of gastric cancer. The treatment options for this tumor are always rapidly evolving, and we will emphasize the medical treatment options available. We hope to outline and explain some of these latest advancements to allow clinicians and future researchers to have a better understanding of this rapidly changing field and allow them to make informed decisions for the care of their patients. ABSTRACT: Gastric cancer is an enigmatic malignancy that has recently been shown to be increasing in incidence globally. There has been recent progress in emerging technologies for the diagnosis and treatment of the disease. Improvements in non-invasive diagnostic techniques with serological tests and biomarkers have led to decreased use of invasive procedures such as endoscopy. A multidisciplinary approach is used to treat gastric cancer, with recent significant advancements in systemic therapies used in combination with cytotoxic chemotherapies. New therapeutic targets have been identified and clinical trials are taking place to assess their efficacy and safety. In this review, we provide an overview of the current and emerging treatment strategies and diagnostic techniques for gastric cancer.