Transcriptional Profiling Reveals Mesenchymal Subtypes of Small Cell Lung Cancer with Activation of the Epithelial-to-Mesenchymal Transition and Worse Clinical Outcomes

SIMPLE SUMMARY: The aim of this study is to discover and characterize novel small cell lung cancer (SCLC) subtypes and further identify their relationship with existing SCLC subtypes. We identified SCLC-M (mesenchymal) tumors as SCLC subtypes that are distinctive of SCLC-I (inflamed) tumors. SCLC-M...

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Detalles Bibliográficos
Autores principales: Cho, Hae Jin, Hong, Soon Auck, Ryu, Daeun, Hong, Sook-Hee, Kim, Tae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688413/
https://www.ncbi.nlm.nih.gov/pubmed/36428693
http://dx.doi.org/10.3390/cancers14225600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688413/
https://www.ncbi.nlm.nih.gov/pubmed/36428693
http://dx.doi.org/10.3390/cancers14225600

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