Cargando…
Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy
SIMPLE SUMMARY: Primary concurrent platinum-based chemoradiation (CRT) is the standard-of-care treatment for locally advanced cervical cancer. However, persistent, recurrent or metastatic disease remains a substantial cause of mortality in women worldwide. Biomarker research can help identify the po...
Autores principales: | Fleischmann, Maximilian, Mandal, Ranadip, Kostova, Izabela, Raab, Monika, Sanhaji, Mourad, Hehlgans, Stephanie, Diefenhardt, Markus, Rödel, Claus, Fokas, Emmanouil, Strebhardt, Klaus, Rödel, Franz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688434/ https://www.ncbi.nlm.nih.gov/pubmed/36428594 http://dx.doi.org/10.3390/cancers14225500 |
Ejemplares similares
-
The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer
por: Mandal, Ranadip, et al.
Publicado: (2022) -
Correction: The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer
por: Mandal, Ranadip, et al.
Publicado: (2023) -
Association of Polo-Like Kinase 3 and PhosphoT273 Caspase 8 Levels With Disease-Related Outcomes Among Cervical Squamous Cell Carcinoma Patients Treated With Chemoradiation and Brachytherapy
por: Fleischmann, Max, et al.
Publicado: (2019) -
Targeting CDK9 for Anti-Cancer Therapeutics
por: Mandal, Ranadip, et al.
Publicado: (2021) -
Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8
por: Helmke, Christina, et al.
Publicado: (2016)