The Association of R-Loop Binding Proteins Subtypes with CIN Implicates Therapeutic Strategies in Colorectal Cancer

SIMPLE SUMMARY: R-Loops, finely regulated by R-Loop binding proteins (RLBPs), play pivotal roles in maintaining genomic stability. By integrated proteogenomic analysis, we identified two RLBPs subtypes with distinct prognostic and therapeutic differences in colorectal cancer (CRC). Cluster-I (CI), c...

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Detalles Bibliográficos
Autores principales: Zhao, Wenchao, Pei, Qian, Zhu, Yongwei, Zhan, Dongdong, Mao, Guo, Wang, Meng, Qiu, Yanfang, Zuo, Ke, Pei, Haiping, Sun, Lun-Quan, Wen, Ming, Tan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688457/
https://www.ncbi.nlm.nih.gov/pubmed/36428700
http://dx.doi.org/10.3390/cancers14225607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688457/
https://www.ncbi.nlm.nih.gov/pubmed/36428700
http://dx.doi.org/10.3390/cancers14225607

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