Cargando…

The Association of R-Loop Binding Proteins Subtypes with CIN Implicates Therapeutic Strategies in Colorectal Cancer

SIMPLE SUMMARY: R-Loops, finely regulated by R-Loop binding proteins (RLBPs), play pivotal roles in maintaining genomic stability. By integrated proteogenomic analysis, we identified two RLBPs subtypes with distinct prognostic and therapeutic differences in colorectal cancer (CRC). Cluster-I (CI), c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Wenchao, Pei, Qian, Zhu, Yongwei, Zhan, Dongdong, Mao, Guo, Wang, Meng, Qiu, Yanfang, Zuo, Ke, Pei, Haiping, Sun, Lun-Quan, Wen, Ming, Tan, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688457/ https://www.ncbi.nlm.nih.gov/pubmed/36428700 http://dx.doi.org/10.3390/cancers14225607

Ejemplares similares

The wages of CIN
por: Yuen, Karen W., et al.
Publicado: (2008)

Predictors of Absent High-grade Cervical Intraepithelial Neoplasia (CIN) in Loop Electrosurgical Excision Procedure Specimens of Patients with Colposcopic Directed Biopsy-Confirmed High-Grade CIN
por: Poomtavorn, Yenrudee, et al.
Publicado: (2019)

Twist1 induces chromosomal instability (CIN) in colorectal cancer cells
por: Khot, Maithilee, et al.
Publicado: (2020)

Tincture Cin Honœ Ferrata
por: Sims, Samuel
Publicado: (1853)

Progression of CIN1/LSIL HPV Persistent of the Cervix: Actual Progression or CIN3 Coexistence
por: Bruno, Maria Teresa, et al.
Publicado: (2021)

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells
por: Lee, Hee-Sheung, et al.
Publicado: (2013)

Are CIN3 risk or CIN3+ risk measures reliable surrogates for invasive cervical cancer risk?
por: Austin, R. Marshall, et al.
Publicado: (2020)

In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain
por: Vittorio, Serena, et al.
Publicado: (2021)

Quantitative Histopathological Analysis of CIN Sections
por: Baak, Jan P. A.
Publicado: (2006)

Quantitative Histopathological Analysis of CIN Sections
por: Guillaud, Martial, et al.
Publicado: (2006)

Evolution of aneuploidy: overcoming the original CIN
por: Storchova, Zuzana
Publicado: (2018)

Up to your NEK2 in CIN
por: Seachrist, Darcie D., et al.
Publicado: (2021)

The adaptive strategies of cells in the face of CIN
por: Storchová, Zuzana
Publicado: (2023)

Bayesian analysis of baseline risk of CIN2 and ≥CIN3 by HPV genotype in a European referral cohort
por: Bonde, Jesper, et al.
Publicado: (2019)

Prevalence of human papillomavirus and subtype distribution in male partners of women with cervical intraepithelial neoplasia (CIN): a systematic review
por: Skoulakis, Anargyros, et al.
Publicado: (2019)

Overexpression of programmed cell death ligand 1 in patients with CIN and its correlation with human papillomavirus infection and CIN persistence
por: Sancakli Usta, Ceyda, et al.
Publicado: (2020)

p53 hides a multitude of CIN
por: Short, Ben
Publicado: (2010)

The CINs of Polo-Like Kinase 1 in Cancer
por: Cunningham, Chelsea E., et al.
Publicado: (2020)

The Regulation of CIN-like TCP Transcription Factors
por: Lan, Jingqiu, et al.
Publicado: (2020)

The Ed. Ef Cin. Med. Jour. Remarks
Publicado: (1889)

Apoptosis as a Barrier against CIN and Aneuploidy
por: Weiss, Johannes G., et al.
Publicado: (2022)

Risks of CIN 2+, CIN 3+, and Cancer by Cytology and Human Papillomavirus Status: The Foundation of Risk-Based Cervical Screening Guidelines
por: Demarco, Maria, et al.
Publicado: (2017)

Loop Electrosurgical Excisional Procedure (LEEP) Done for Discrepancy: Does the Time from HGSIL Affect Pathologic Grade of CIN in LEEP Specimen?
por: Moreni, Sue L., et al.
Publicado: (2010)

Underdiagnosis of cervical intraepithelial neoplasia (CIN) 2 or Worse Lesion in Women with a Previous Colposcopy-Guided Biopsy Showing CIN 1
por: Souza, Carlos André Scheler de, et al.
Publicado: (2017)

Original CIN: reviewing roles for APC in chromosome instability
por: Rusan, Nasser M., et al.
Publicado: (2008)

CIN III Diagnosed following Surgical Termination of Pregnancy
por: Mackenzie, Ciara, et al.
Publicado: (2014)

Predictive Testing of Early CIN Behaviour by Molecular Biomarkers
por: Baak, Jan P. A., et al.
Publicado: (2005)

Evaluating HPV‐negative CIN2+ in the ATHENA trial
por: Petry, Karl Ulrich, et al.
Publicado: (2016)

Long Term Effectiveness of Photodynamic Therapy for CIN Treatment
por: Inada, Natalia Mayumi, et al.
Publicado: (2019)

CinA mediates multidrug tolerance in Mycobacterium tuberculosis
por: Kreutzfeldt, Kaj M., et al.
Publicado: (2022)

The progress in our understanding of CIN in breast cancer research
por: Liao, Yu-Yang, et al.
Publicado: (2023)

A survey of CIN measures across mechanistic models
por: Lynch, Andrew R., et al.
Publicado: (2023)

Exploring Molecular Contacts of MUC1 at CIN85 Binding Interface to Address Future Drug Design Efforts
por: Gulotta, Maria Rita, et al.
Publicado: (2021)

Chronical cervical infections and dysplasia (CIN I, CIN II): Vaginal vitamin D (high dose) treatment: A new effective method?
por: Schulte-Uebbing, C, et al.
Publicado: (2014)

Matrix Stiffness and Colorectal Cancer
por: Liu, Chongshun, et al.
Publicado: (2020)

Inhibition of CIN85-Mediated Invasion by a Novel SH3 Domain Binding Motif in the Lysyl Oxidase Propeptide
por: Sato, Seiichi, et al.
Publicado: (2013)

Efficacy of cervical intrarepithelial neoplasia (CIN) treatment by cold coagulation.
por: Zawislak, A., et al.
Publicado: (2003)

Crystal Structure of Cindoxin, the P450cin Redox Partner
por: Madrona, Yarrow, et al.
Publicado: (2014)

Alcohol Consumption and Viral Load Are Synergistically Associated with CIN1
por: Min, Kyung-Jin, et al.
Publicado: (2013)

The Fuss Over Lipo“fuss”cin: Not All Autofluorescence is the Same
por: Sainz, B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_etq8g1pbn5a1ltnn1rmlefunlp