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JAG1 Intracellular Domain Enhances AR Expression and Signaling and Promotes Stem-like Properties in Prostate Cancer Cells

SIMPLE SUMMARY: The expression of androgen receptor variants (AR-Vs) is associated with the development of advanced castration-resistant prostate cancers (CRPCs), while prostate cancer stem cells (PCSCs) have been evaluated as the most dangerous malignant seeding cells. In this study, we found that...

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Detalles Bibliográficos
Autores principales: Tran, Tuyen Thanh, Lee, Keesook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688638/
https://www.ncbi.nlm.nih.gov/pubmed/36428807
http://dx.doi.org/10.3390/cancers14225714