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Lipid Dys-Homeostasis Contributes to APOE4-Associated AD Pathology

The association of the APOE4 (vs. APOE3) isoform with an increased risk of Alzheimer’s disease (AD) is unequivocal, but the underlying mechanisms remain incompletely elucidated. A prevailing hypothesis incriminates the impaired ability of APOE4 to clear neurotoxic amyloid-β peptides (Aβ) from the br...

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Detalles Bibliográficos
Autores principales:	Lazar, Adina-Nicoleta, Hanbouch, Linda, Boussicaut, Lydie, Fourmaux, Baptiste, Daira, Patricia, Millan, Mark J., Bernoud-Hubac, Nathalie, Potier, Marie-Claude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9688773/ https://www.ncbi.nlm.nih.gov/pubmed/36429044 http://dx.doi.org/10.3390/cells11223616

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